Ancient Roman historians (non-Christian) relate the first wholesale
massacres of Christians by the Roman government as follows: In the year
64, much of the city of Rome burned. It was widely speculated that the
Emperor Nero had ordered the fire in order that he might rebuild to his
fancy. In order to divert suspicion from himself, Nero accused the
Christians of setting the fires, and had many of them put to death in
various cruel ways: eaten in the arena by wild beasts, covered with pitch
and burned as torches to light the Emperor's nightly revels, and so on.
The persecution appears to have been confined to Rome.
O Almighty God, by whose grace and power thy holy martyrs at Rome in the days of the Emperor Nero triumphed over suffering and were faithful even unto death: Grant us, who now remember them with thanksgiving, to be so faithful in our witness to thee in this world, that we may receive with them the crown of life; through Jesus Christ our Lord, who with thee and the Holy Spirit liveth and reigneth, one God, for ever and ever.
O Almighty God, by whose grace and power your holy martyrs at Rome in the days of the Emperor Nero triumphed over suffering and were faithful even unto death: Grant us, who now remember them with thanksgiving, to be so faithful in our witness to you in this world, that we may receive with them the crown of life; through Jesus Christ our Lord, who lives and reigns with you and the Holy Spirit, one God, for ever and ever.